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- Color: Black
- Parts: 30 DAYS WARRANTY
- Labor: 30 DAYS WARRANTY
- Model #: Newegg_Delete
- $18.99 –
- $7.99 Shipping
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Adesso iMouse E10 - Vertical Ergonomic Optical 6-Button 2.4 GHz RF Wireless Mouse - Right Hand Orientation, Black
- Hand Orientation: Right Hand
- Resolution (DPI): 2000 dpi
- Distance: Up to 30 feet
- Operating System Supported: Windows 8/ 7/ Vista/ XP/ 2000, Mac OS X & above
- Model #: IMOUSE E10
- $68.99 –
- Free Shipping
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Adesso iMouseE1 Vertical illuminated Ergonomic USB mouse
- Resolution (DPI): 1600 dpi
- Package Contents: iMouse E1 - Vertical Ergonomic Illuminated Mouse Quick Start Guide
- Model #: iMouse E1
- $57.99 –
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- $26.79 –
- More options from $24.43 - $56.28
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Adesso iMouse S8L - USB Illuminated Retractable Mini Mouse
- Resolution (DPI): 1600 dpi
- Package Contents: iMouse S8L - USB Illuminated Retractable Mini Mouse Quick Start Guide
- Parts: 1 Year
- Model #: IMOUSE S8L
- $17.99 –
- More options from $17.99 - $31.38
- $2.99 Shipping
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Kensington Orbit Trackball Mouse with Scroll Ring (K75327WW)
- Model #: 85896753278
- $59.99 –
- More options from $59.99 - $93.21
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- Brand: lenovo
- Name: Essential USB Mouse
- Model: 4Y50R20863
- Color: Black
- Model #: 4Y50R20863
- $26.99
- $19.99 –
- Save: 25%
- More options from $19.99 - $65.11
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- Brand: lenovo
- Model: 4Y50R20864
- Color: Black
- Type: Wireless
- Model #: 4Y50R20864
- $21.78 –
- More options from $20.55 - $69.37
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Targus AMB582GL Black 1 x Wheel Dual (RF / Bluetooth Wireless) Midsize Comfort Multi-Device Antimicrobial Wireless Mouse
- Resolution (DPI): 2400 dpi
- Power Supply: 1 x AA Battery
- Model #: AMB582GL
- $39.99
- $31.11 –
- Save: 22%
- More options from $31.11 - $93.71
- $10.99 Shipping
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- Resolution (DPI): 1000 dpi
- Parts: 30 DAYS WARRANTY
- Labor: 30 DAYS WARRANTY
- Model #: 15VVH
- $19.99 –
- More options from $19.99 - $35.99
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Targus Antimicrobial Ergo Wireless Mouse - BlueTrace - Wireless - Radio Frequency - 2.40 GHz - Black - USB Type A - 1600 dpi - Scroll Wheel, Thumbwheel - 7 Button(s) - Right-handed Only - AMW584GL
- Hand Orientation: Right Hand
- Resolution (DPI): 1600 dpi
- Power Supply: 2 x AA Batteries
- Operating Time: 667hrs based on 2800mA battery capacity
- Model #: AMW584GL
- $52.55 –
- More options from $52.55 - $118.34
- $10.99 Shipping
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- $33.99 –
- More options from $31.55 - $33.99
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Kensington 72352 Orbit Wireless Mobile Trackball
- Brand: Kensington
- Color: Black
- Tracking Method: TrackBall
- Features: Pointing Device Connectivity Technology: WirelessPointing Device Wireless Technology: Radio FrequencyScroller Type: TrackballErgonomic Fit: SymmetricalPointing Device Host Interface: USBColor: BlackPackage Contents: Orbit 72352 TrackballUSB Receiver2 x AA BatteriesWarranty CardDevice Supported: ComputerPost-consumer-waste%: 0%Assembly Required: NoGreen Compliant: YesGreen Compliance Certificate/Authority: WEEECountry of Origin: ChinaLimited Warranty: 5 Year
- Model #: 72352
- $63.99 –
- Free Shipping
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- Hand Orientation: Right Hand
- Resolution (DPI): 3-level adjustable (default at 2400,1600,800)
- Power Supply: 1 x AA Battery
- Operating Time: Up to 12 months
- Model #: 4Y51C33792
- $72.77 –
- More options from $72.77 - $133.22
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- $32.99
- $25.99 –
- Save: 21%
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CORDED NOTEBOOK OPTICAL MOUSE
- Parts: 1 Year
- Model #: 99741
- $11.99 –
- More options from $11.99 - $27.22
- $2.99 Shipping
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Lenovo ThinkPad Bluetooth Silent Mouse
- Brand: lenovo
- Model: 4Y50X88822
- Color: Black
- Part Number: 4Y50X88822
- Model #: 4Y50X88822
- $57.62 –
- More options from $57.62 - $80.40
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- $15.11 –
- More options from $6.99 - $22.22
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- Brand: HP
- Type: RF Wireless
- Parts: 1 Year
- Model #: 4E407UT#ABL
- $21.78 –
- More options from $18.99 - $49.99
- Free Shipping
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Hippus L2WB-LC Black 3 Buttons 1 x Wheel USB Wired Handshoe Mouse Light Click, Right Hand, Wired, Large
- Hand Orientation: Right Hand
- Resolution (DPI): 1500 dpi
- Model #: L2WB-LC
- $176.99 –
- Free Shipping
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Kensington K64325 Expert Trackball Mouse
- Operating System Supported: Mac OS, Vista, Windows 10, Windows 7, Windows 8, XP
- Version: Wired
- Model #: k64325
- $102.99 –
- More options from $95.55 - $199.18
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HP 425 Mouse - Wireless - Bluetooth - Black - 4000 dpi - Tilt Wheel - 7 Button(s) - 6 Programmable Button(s)
- Part Number: 7M1D5AA#ABA
- Features: HP 425 Programmable Bluetooth Mouse
- Model #: 7M1D5AA#ABA
- $50.88 –
- More options from $50.88 - $53.88
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Adesso iMouseE10 2.4 GHz RF wireless Vertical Ergonomic mouse with DPI switch button
- Resolution (DPI): 2000 dpi
- Power Supply: AAA
- Distance: Up to 30 feet
- System Requirement: USB Port Operating Systems: Windows 8 Windows 7 Windows Vista Windows XP Windows 2000 Mac OS X and Above
- Model #: IMOUSEE10
- $69.99
- $66.22 –
- Save: 5%
- More options from $66.22 - $75.22
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Verbatim 97995 Wireless Multi-Trac Blue LED Optical Mouse (Red)
- Power Supply: 1 x AA Battery
- Operating System Supported: Windows 8, 7, XP, 2000, Vista, Mac OS 10.4.X and higher
- System Requirement: USB port
- Package Contents: 37121T
- Model #: 97995
- $26.22 –
- More options from $26.22 - $32.22
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Adesso iMouse W3 Waterproof Wired Mouse with Magnetic Scroll Wheel IP67 Rated Optical Sensor 1000 DPI USB Connection for Medical Industrial Maritime and Office Environments Black
- Brand: ADESSO
- Name: iMouse W3
- Color: Black
- Buttons: 4
- Model #: IMOUSEW3
- $48.97 –
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- Hand Orientation: Both Hands
- Resolution (DPI): On-the-fly adjustment (2400, 1600, 800)
- Power Supply: 380mAh integrated rechargeable battery Charging Port: USB-C charging Charging Cable: USB-A power delivery cable, 0.5m
- Operating Time: Quick Charge: 15 minutes charge, 1 week battery
- Model #: GY51C21210
- $78.99
- $63.99 –
- Save: 18%
- More options from $63.99 - $118.78
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EXPERT MOUSE OPTICAL
- Parts: 5 Year
- Model #: 64325
- $86.99 –
- More options from $86.99 - $190.45
- $3.99 Shipping
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- Brand: Microsoft Surface
- Type: Wired
- Model #: 3YR-00001
- $95.11 –
- More options from $95.11 - $138.22
- $10.99 Shipping
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Verbatim Universal Wired Optical Mouse Black (70733) VTM70733
- Brand: Verbatim
- Color: Black
- Type: Wired
- Parts: 1 Year
- Model #: 70733
- $16.54 –
- More options from $16.54 - $25.22
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Verbatim Multi-Device Wireless Rechargeable Optical Mouse - Black - Optical - Wireless - Bluetooth/Radio Frequency - 2.40 GHz - Yes - Black - USB
- Parts: 1 Year
- Model #: 70750
- $32.30 –
- More options from $32.30 - $41.58
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Evoluent VM4R VerticalMouse 4 Ergonomic USB Mouse Med to Large Right Hand
- Hand Orientation: Right Hand
- Version: Wired
- Parts: 1 year limited
- Model #: VM4R
- $142.67 –
- More options from $142.67 - $163.95
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Limited time offer, ends 11/01
- Brand: HP
- Name: HP 125 Wired Mouse
- Model: M27537-001
- Color: Black
- Model #: 265A9UT
- $24.70 –
- More options from $22.55 - $66.47
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SEAL SHIELD Storm Tm-Medical Grade STM042 Black Wired Optical Mouse
- Parts: 30 DAYS WARRANTY
- Labor: 30 DAYS WARRANTY
- Model #: STM042
- $114.22 –
- More options from $114.22 - $178.37
- $10.99 Shipping
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Fantastic Alternating Light High Accuracy USB 2.0 7-Button Wired Game Mouse 5500 DPI High Accuracy Gaming Mouse
- Hand Orientation: Right Hand
- Resolution (DPI): 5500 dpi
- Version: Standard
- Model #: E000096-1
- $17.95 –
- Free Shipping
Wireless Mice, Optical Mice, Laser Mice and Trackball Mice
At Newegg you can choose from a massive selection of computer mice from industry leading manufacturers including wired and wireless products, as well as sleek space-saving designs for notebook computers and ergonomic mice for the utmost in user comfort and gaming performance regardless of hand-orientation.
Brands featured at Newegg include Microsoft, Kensington, Logitech, Targus and others in configurations of RF wireless, Fast RF wireless, Bluetooth Wireless, and standard PS/2 and USB wired interfaces.
With a mouse to fit every computer performance need Newegg has what you need. For more information, please see our Computer Mouse Buying Guide.
Bestselling Mouse Reviews:
Anonymous
9/8/2026 9:12:20 PM
Great wireless mouse
“ My old one was also a Microsoft mouse, but it came with Bluetooth only. ”
Microsoft GMF-00176 White Wireless Mobile 3500 Mouse - BlueTrack - Wireless - Radio Frequency - USB - 1000 dpi - Scroll Wheel - 3 Button(s) - SymmetricalJames A.
7/12/2026 3:54:07 PM
Effective and affordable.
“ It's a perfectly functional 5-button optical mouse with a scroll wheel at a reasonable price. ”
Perixx PERIMICE-508 Wired Programmable Vertical Ergonomic Mouse, Natural Vertical Mouse with 5 Programmable Buttons and 2 Level DPI, Right HandedVann L.
3/7/2026 1:20:10 PM
A Ergo Mouse Rechargeable
“ Oh and I love Logitech mouse they are the best for me. ”
Logitech MX Vertical Wireless Mouse – Advanced Ergonomic Design Reduces Muscle Strain, Control and Move Content Between 3 Windows and Apple Computers (Bluetooth or USB), Rechargeable, GraphiteJAMIE W.
2/6/2026 8:29:20 AM
Comfortable
“ If you don't need the tilt feature on the center wheel, this is a comfortable mouse. ”
Logitech M650 Signature wireless Mouse 910-006231 Graphite 5 Buttons 1 x Wheel Wireless MouseM.K.
1/5/2026 2:18:59 PM
Durable and energy efficient
“ I definitely recommend this mouse for people looking to improve their ergonomics at their desks. ”
Logitech ERGO M575 Wireless Trackball Mouse - Easy thumb control, precision and smooth tracking, ergonomic comfort design, for Windows, PC and Mac with Bluetooth and USB capabilities - Off WhiteAnonymous
10/15/2025 3:27:31 AM
plug and play
“ a well priced, easy to install and use mouse. ”
Fantech DeathAdder Essential Wired Gaming Mouse, Mechanical Switch,6400dpi,6 programmable buttons, Five High-speed Response Buttons, BlackDon M.
10/13/2025 2:14:10 PM
Comfortable, reliable, long-lasting solution for hand and wrist pain
“ The vertical mouse helps me prevent repetitive strain injury (RSI), and as vertical mice go, I think this is the best. ”
Logitech MX Vertical Wireless Mouse – Advanced Ergonomic Design Reduces Muscle Strain, Control and Move Content Between 3 Windows and Apple Computers (Bluetooth or USB), Rechargeable, Graphite