Wireless Mice, Optical Mice, Laser Mice and Trackball Mice

At Newegg you can choose from a massive selection of computer mice from industry leading manufacturers including wired and wireless products, as well as sleek space-saving designs for notebook computers and ergonomic mice for the utmost in user comfort and gaming performance regardless of hand-orientation.

Brands featured at Newegg include Microsoft, Kensington, Logitech, Targus and others in configurations of RF wireless, Fast RF wireless, Bluetooth Wireless, and standard PS/2 and USB wired interfaces.

With a mouse to fit every computer performance need Newegg has what you need. For more information, please see our Computer Mouse Buying Guide.

Bestselling Mouse Reviews:

Anonymous

9/8/2026 9:12:20 PM

Great wireless mouse

“ My old one was also a Microsoft mouse, but it came with Bluetooth only. ”

Microsoft GMF-00176 White Wireless Mobile 3500 Mouse - BlueTrack - Wireless - Radio Frequency - USB - 1000 dpi - Scroll Wheel - 3 Button(s) - Symmetrical

James A.

7/12/2026 3:54:07 PM

Effective and affordable.

“ It's a perfectly functional 5-button optical mouse with a scroll wheel at a reasonable price. ”

Perixx PERIMICE-508 Wired Programmable Vertical Ergonomic Mouse, Natural Vertical Mouse with 5 Programmable Buttons and 2 Level DPI, Right Handed

Vann L.

3/7/2026 1:20:10 PM

A Ergo Mouse Rechargeable

“ Oh and I love Logitech mouse they are the best for me. ”

Logitech MX Vertical Wireless Mouse – Advanced Ergonomic Design Reduces Muscle Strain, Control and Move Content Between 3 Windows and Apple Computers (Bluetooth or USB), Rechargeable, Graphite

JAMIE W.

2/6/2026 8:29:20 AM

Comfortable

“ If you don't need the tilt feature on the center wheel, this is a comfortable mouse. ”

Logitech M650 Signature wireless Mouse 910-006231 Graphite 5 Buttons 1 x Wheel Wireless Mouse

M.K.

1/5/2026 2:18:59 PM

Durable and energy efficient

“ I definitely recommend this mouse for people looking to improve their ergonomics at their desks. ”

Logitech ERGO M575 Wireless Trackball Mouse - Easy thumb control, precision and smooth tracking, ergonomic comfort design, for Windows, PC and Mac with Bluetooth and USB capabilities - Off White

Anonymous

10/15/2025 3:27:31 AM

plug and play

“ a well priced, easy to install and use mouse. ”

Fantech DeathAdder Essential Wired Gaming Mouse, Mechanical Switch,6400dpi,6 programmable buttons, Five High-speed Response Buttons, Black

Don M.

10/13/2025 2:14:10 PM

Comfortable, reliable, long-lasting solution for hand and wrist pain

“ The vertical mouse helps me prevent repetitive strain injury (RSI), and as vertical mice go, I think this is the best. ”

Logitech MX Vertical Wireless Mouse – Advanced Ergonomic Design Reduces Muscle Strain, Control and Move Content Between 3 Windows and Apple Computers (Bluetooth or USB), Rechargeable, Graphite

Mouse

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Wireless Mice, Optical Mice, Laser Mice and Trackball Mice

Bestselling Mouse Reviews: