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ASUS PRIME TRX40-PRO S sTRX4 AMD TRX40 SATA 6Gb/s ATX AMD Motherboard

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AMD TRX40
AMD Socket sTRX4 for 3rd Gen AMD Ryzen Threadripper Series Desktop Processors
DDR4 4666(O.C.)/ 4600(O.C)/ 4400(O.C)/ 4333(O.C.)/ 4266(O.C.)/ 4133(O.C.)/ 3800(O.C.)/ 3733(O.C.)/ 3466(O.C.)/ 3400(O.C.)/ 3200/ 2933/ 2800/ 2666/ 2400/ 2133 MHz ECC and non-ECC, Un-buffered Memory

Overview

Specs

Reviews

Multi-GPU Support: Supports NVIDIA Quad-GPU SLI Technology Supports NVIDIA 2-Way SLI Technology Supports AMD Quad-GPU CrossFireX Technology Supports AMD 2-Way CrossFireX
Technology Special Features: ASUS Dual Intelligent Processors 5-Way Optimization by Dual Intelligent
Processors 5: - 5-Way Optimization tuning key perfectly consolidates TPU, EPU, DIGI+ VRM, Fan Expert 4, and Turbo App ASUS SafeSlot - Protect your graphics card
Investment AURA: - Aura RGB Strip Headers - Aura Lighting Effects Synchronization with compatible ASUS ROG devices - Addressable Gen 2
Header ASUS Exclusive Features: - AI Suite 3 - Ai Charger -
Onboard Button: Power - ASUS UEFI BIOS EZ Mode featuring friendly graphics user interface - Turbo LAN - Crystal Sound 3 - Armoury Crate - Pre-mounted I/O Shield ASUS Quiet Thermal Solution: - Stylish Design Heat-pipe solution - Stylish Fanless Design with M. 2 Heat-sink solution - ASUS Fan Xpert 4
ASUS EZ DIY: - ASUS EZ Flash 3 - ASUS USB BIOS FlashBack - ASUS UEFI BIOS EZ Mode -
Multi-language BIOS ASUS Q-Design: - ASUS Q-Code - ASUS Q-LED (CPU, DRAM, VGA, Boot Device LED) - ASUS Q-Slot - ASUS Q-DIMM -
ASUS Q-Connector BIOS: 1 x 128MB Flash ROM, UEFI AMI BIOS, PnP, WfM 2.0, SM BIOS 3.2, ACPI 6.2
Manageability: WfM 2.0, WOL by PME, PXE
Operating System: Windows 10 64-bit

Model
Brand	ASUS
Series	TRX40
Model	PRIME TRX40-PRO S

Supported CPU
CPU Socket Type	sTRX4
CPU Type	Ryzen Threadripper Series

Chipsets
Chipset	AMD TRX40

Memory
Number of Memory Slots	8x288pin (DDR4)
Memory Standard	DDR4 4666(O.C.)/ 4600(O.C)/ 4400(O.C)/ 4333(O.C.)/ 4266(O.C.)/ 4133(O.C.)/ 3800(O.C.)/ 3733(O.C.)/ 3466(O.C.)/ 3400(O.C.)/ 3200/ 2933/ 2800/ 2666/ 2400/ 2133 MHz ECC and non-ECC, Un-buffered Memory
Maximum Memory Supported	256GB
Channel Supported	Quad Channel

Expansion Slots
PCI Express 4.0 x16	3rd Gen AMD Ryzen Threadripper Desktop Processors - 3 x PCIe 4.0 x16 Safeslots (supports x16/x16/x16 mode)* * Recommend you to install add-on cards on (PCIEX16_1 and PCIEX16_2) or (PCIEX16_1 and PCIEX16_3) to enjoy 2 way SLI or CrossFireX.
PCI Express x4	AMD TRX40 chipset: 1 x PCIe 4.0 (x4 mode)
Other Slots	1 x M.2 Socket (Key E), supports type 2230 PCIe Wi-Fi/BT module* * The Wi-Fi/BT module is purchased separately

Storage Devices
Serial ATA (SATA)	8 x SATA 6Gb/s
M.2	3rd Gen AMD Ryzen Threadripper Series Desktop processors: 2 x M.2 Socket 3, with M key, type 2242/2260/2280/22110 storage devices support (PCIe 4.0 x4 mode) AMD TRX40 chipset: 1 x M.2 Socket 3, with vertical M key, type 2242/2260/2280/22110 storage devices support (SATA & PCIe 4.0 x4 mode)
SATA RAID	0/1/10

Onboard Audio
Audio Chipset	Realtek ALC S1220 High Definition Audio CODEC featuring Crystal Sound 3
Audio Channels	8 Channels

Onboard LAN
LAN Chipset	Intel i211AT
Max LAN Speed	1Gbps

Rear Panel Ports
Back I/O Ports	1 x LAN (RJ45) port(s) 4 x USB 3.2 Gen 2 (teal blue) (3 x Type-A + 1 x Type-C) (one port can be switched to USB BIOS FlashBack) 6 x USB 3.2 Gen 1 (blue) 1 x Optical S/PDIF out 5 x Audio jack(s) 1 x USB BIOS FlashBack Button(s)

Internal I/O Connectors
Onboard USB	1 x USB 3.2 Gen 2 front panel Type-C connector 2 x USB 3.2 Gen 1 connectors support additional 4 USB ports (19-pin) 2 x USB 2.0 connectors support additional 4 USB ports
Other Connectors	1 x 4-Pin W_PUMP+ connector 1 x 4-Pin AIO_PUMP fan connector 1 x 4-Pin CPU Fan connector 1 x 4-Pin CPU_OPT fan connector 1 x 3-pin Chipset fan connector 3 x 4-Pin Chassis Fan connectors 1 x 2-pin Thermal sensor header 2 x Aura Addressable Gen2 headers 2 x Aura RGB headers 1 x NODE connector 1 x Front panel audio connector (AAFP) 1 x System panel connector with FlexKey 1 x Q_Code 1 x Clear CMOS header 1 x Power-on button

Physical Spec
Form Factor	ATX
LED Lighting	RGB
Dimensions (W x L)	12.0" x 9.6"
Power Pin	1 x 24-pin EATX Power connector(s) 2 x 8-pin ATX 12V Power connector(s)

Software Feature
Windows 11	Supported

Features
Features	Multi-GPU Support: Supports NVIDIA Quad-GPU SLI Technology Supports NVIDIA 2-Way SLI Technology Supports AMD Quad-GPU CrossFireX Technology Supports AMD 2-Way CrossFireX Technology Special Features: ASUS Dual Intelligent Processors 5-Way Optimization by Dual Intelligent Processors 5: - 5-Way Optimization tuning key perfectly consolidates TPU, EPU, DIGI+ VRM, Fan Expert 4, and Turbo App ASUS SafeSlot - Protect your graphics card Investment AURA: - Aura RGB Strip Headers - Aura Lighting Effects Synchronization with compatible ASUS ROG devices - Addressable Gen 2 Header ASUS Exclusive Features: - AI Suite 3 - Ai Charger - Onboard Button: Power - ASUS UEFI BIOS EZ Mode featuring friendly graphics user interface - Turbo LAN - Crystal Sound 3 - Armoury Crate - Pre-mounted I/O Shield ASUS Quiet Thermal Solution: - Stylish Design Heat-pipe solution - Stylish Fanless Design with M.2 Heat-sink solution - ASUS Fan Xpert 4 ASUS EZ DIY: - ASUS EZ Flash 3 - ASUS USB BIOS FlashBack - ASUS UEFI BIOS EZ Mode - Multi-language BIOS ASUS Q-Design: - ASUS Q-Code - ASUS Q-LED (CPU, DRAM, VGA, Boot Device LED) - ASUS Q-Slot - ASUS Q-DIMM - ASUS Q-Connector BIOS: 1 x 128MB Flash ROM, UEFI AMI BIOS, PnP, WfM2.0, SM BIOS 3.2, ACPI 6.2 Manageability: WfM 2.0, WOL by PME, PXE Operating System: Windows 10 64-bit

Additional Information
First Listed on Newegg	August 04, 2026

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ASUS PRIME TRX40-PRO S sTRX4 AMD TRX40 SATA 6Gb/s ATX AMD Motherboard

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Item#: 9SIC3VJM3G5761

Meet Your Seller

ASUS PRIME TRX40-PRO S sTRX4 AMD TRX40 SATA 6Gb/s ATX AMD Motherboard

Refurbished

Learn more about the ASUS PRIME TRX40-PRO S

Customer Reviews of the ASUS PRIME TRX40-PRO S

Warranty & Returns

Warranty, Returns, And Additional Information

Warranty

Return Policies

Manufacturer Contact Info